Interstate 380

Interstate 380 may refer to:

Interstate 380 (California), a spur from Interstate 280 to U.S. Highway 101 and the San Francisco International Airport
Interstate 380 (Iowa), a spur from Interstate 80 that goes through Cedar Rapids, Iowa and eventually ends in Waterloo, Iowa
Interstate 380 (Pennsylvania), a connection between Interstate 80 and Interstate 81 south of Scranton, Pennsylvania

This article includes a list of roads, streets, highways, or other routes that are associated with the same title.
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